Fig. 10From: Pseudoginsengenin DQ exerts antitumour activity against hypopharyngeal cancer cells by targeting the HIF-1α-GLUT1 pathwayPDQ affected the distribution of GLUT1 and weakened its clustering on the membrane. a, c dSTORM imaging of GLUT1 on FaDu cell membrane without treatment (a) or with 100 μM PDQ treatment (c). b, d Magnified regions of GLUT1 corresponding to the white box in (a) and (c). Scale bars, 5 μm in (b) and (d), 1 μm in (b) and (d). e The number of GLUT1 localizations per μm2 on control and PDQ-treated cell membranes. f The number of clusters per μm2. g The distribution of cluster diameter. h The distribution of localization number per cluster. Data shown in e–h are means ± s.d.. All statistics were obtained from 30 cells in five independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, two-tailed unpaired t-testBack to article page