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Fig. 5 | Cancer Cell International

Fig. 5

From: β-Catenin/LEF-1 transcription complex is responsible for the transcriptional activation of LINC01278

Fig. 5

LINC01278 promotes the ubiquitin–proteasome degradation of β-catenin. The expression of Wnt/β-catenin signal targets (CCND2, CyclinD1, MYC, and SOX4) in TPC-1 (A) and BCPAP (B) cells which were transfected with LINC01278 siRNA (LINC-KD) or overexpression plasmid (LINC01278). C The protein expression of β-catenin in TPC-1 and BCPAP cells which were treated with a proteasome inhibitor (MG132) and LINC01278 expression plasmid. *P < 0.05

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