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Fig. 2 | Cancer Cell International

Fig. 2

From: MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2

Fig. 2

Inhibition of papillary thyroid cancer (PTC) cell proliferation, migration, and invasion by miR-613 in vitro. K1, TPC-1, and BCPAP cells were transfected with miR-613 mimics or miR-NC. a Significant inhibition of PTC cell growth at 48, 72, and 96 h owing to miR-613 restoration. b, c Inhibition of PTC cell migration ability via miR-613 restoration based on wound healing assays. Left, representative images showing the migration of three PTC cells in six-well culture plates (b). Right, quantification of the cell migration distances corresponding to three PTC cells (c). d, e Restoration of miR-613 inhibited PTC cell invasion. Images of cells that migrated to the bottom chamber (d) and calculated number of invasion cells (e). * p < 0.05, **p < 0.01, *** p < 0.001, **** p < 0.0001

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