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Table 1 List of GO enrichment analysis performed on GSE42352 (gene enrichment number Top10) and target (gene enrichment number Top10) database co-expressed differential genes by clusterProfiler package

From: PODN is a prognostic biomarker and correlated with immune infiltrates in osteosarcoma

Dataset Ontology ID Description P.adjust Count
GSE42352 BP GO:0030198 Extracellular matrix organization 4.25E−15 22
GSE42352 BP GO:0043062 Extracellular structure organization 4.25E−15 22
GSE42352 BP GO:0019882 Antigen processing and presentation 1.98E−10 15
GSE42352 BP GO:0002478 Antigen processing and presentation of exogenous peptide antigen 8.65E−10 13
GSE42352 BP GO:0019884 Antigen processing and presentation of exogenous antigen 1.25E−09 13
GSE42352 BP GO:0048002 Antigen processing and presentation of peptide antigen 1.79E−09 13
GSE42352 BP GO:0034341 Response to interferon-gamma 3.09E−09 13
GSE42352 BP GO:0071346 Cellular response to interferon-gamma 1.19E−08 12
GSE42352 BP GO:0002697 Regulation of immune effector process 0.000287702 12
GSE42352 BP GO:0043312 Neutrophil degranulation 0.00042594 12
GSE42352 CC GO:0062023 Collagen-containing extracellular matrix 1.39E−19 26
GSE42352 CC GO:0010008 Endosome membrane 9.35E−07 14
GSE42352 CC GO:0030139 Endocytic vesicle 4.96E−08 13
GSE42352 CC GO:0005765 Lysosomal membrane 2.61E−07 13
GSE42352 CC GO:0098852 Lytic vacuole membrane 2.61E−07 13
GSE42352 CC GO:0005774 Vacuolar membrane 1.09E−06 13
GSE42352 CC GO:0042611 MHC protein complex 1.00E−17 11
GSE42352 CC GO:0005581 Collagen trimer 1.39E−11 11
GSE42352 CC GO:0030666 Endocytic vesicle membrane 1.26E−08 11
GSE42352 CC GO:0030133 Transport vesicle 2.34E−05 11
GSE42352 MF GO:0005201 Extracellular matrix structural constituent 3.04E−17 18
GSE42352 MF GO:0033218 Amide binding 1.06E−08 15
GSE42352 MF GO:0042277 Peptide binding 1.06E−08 14
GSE42352 MF GO:0005518 Collagen binding 1.21E−10 10
GSE42352 MF GO:0004175 Endopeptidase activity 0.010282087 8
GSE42352 MF GO:0042605 Peptide antigen binding 1.02E−08 7
GSE42352 MF GO:0019838 Growth factor binding 8.98E−05 7
GSE42352 MF GO:0003823 Antigen binding 0.000230162 7
GSE42352 MF GO:0005539 Glycosaminoglycan binding 0.001734373 7
GSE42352 MF GO:1901681 Sulfur compound binding 0.002670804 7
Target-OS BP GO:0030198 Extracellular matrix organization 6.15E−12 41
Target-OS BP GO:0043062 Extracellular structure organization 6.15E−12 41
Target-OS BP GO:0031589 Cell-substrate adhesion 2.67E−07 33
Target-OS BP GO:0001655 Urogenital system development 0.000137365 27
Target-OS BP GO:0034329 Cell junction assembly 0.010818905 25
Target-OS BP GO:0072001 Renal system development 0.00046375 24
Target-OS BP GO:0001503 Ossification 0.014822976 24
Target-OS BP GO:0001822 Kidney development 0.00057211 23
Target-OS BP GO:0007178 Transmembrane receptor protein serine/threonine kinase signaling pathway 0.00844363 23
Target-OS BP GO:0030111 Regulation of Wnt signaling pathway 0.016578746 22
Target-OS CC GO:0062023 Collagen-containing extracellular matrix 1.28E−09 38
Target-OS CC GO:0005925 Focal adhesion 2.57E−09 37
Target-OS CC GO:0030055 Cell-substrate junction 2.83E−09 37
Target-OS CC GO:0031252 Cell leading edge 9.36E−05 28
TargetOS CC GO:0005743 Mitochondrial inner membrane 0.001986238 27
Target-OS CC GO:0005759 Mitochondrial matrix 0.043195064 22
Target-OS CC GO:0031253 Cell projection membrane 0.002293285 21
Target-OS CC GO:0045121 Membrane raft 0.003431572 20
Target-OS CC GO:0098857 Membrane microdomain 0.003431572 20
Target-OS CC GO:0098589 Membrane region 0.005357409 20
Target-OS MF GO:0050839 Cell adhesion molecule binding 1.46E−08 43
Target-OS MF GO:0005201 Extracellular matrix structural constituent 3.19E−08 23
Target-OS MF GO:0005178 Integrin binding 2.43E−05 17
Target-OS MF GO:0019838 Growth factor binding 0.00016495 16
Target-OS MF GO:0030020 Extracellular matrix structural constituent conferring tensile strength 0.00016495 9
Target-OS MF GO:0003779 Actin binding 0.000286309 30
Target-OS MF GO:0048407 Platelet-derived growth factor binding 0.000577035 5
Target-OS MF GO:0045296 Cadherin binding 0.001118768 24
Target-OS MF GO:0051015 Actin filament binding 0.002243868 17
Target-OS MF GO:0008237 Metallopeptidase activity 0.029742453 14