Table 1 Clinical characteristics and parameters of patients with or without HT

Total number of patients

30

189

Age, years (range)

50.8 ± 6.2 (26–86)

51.2 ± 14.0 (22–71)

0.047

ECOG (0–1/ ≥ 2)

28/2

184/5

0.149

LDH, U/L (mean ± SD)

279 ± 122

231 ± 119

0.136

Bone marrow involvement

11(36.6%)

67(35.4%)

0.510

Area of enlarged lymph nodes (≥ 4)

16(53.3%)

108(52.9%)

0.601

HGB, g/L (mean ± SD)

132.5 ± 21.2

135.4 ± 18.0

0.470

Fibrinogen, g/L (mean ± SD)

3.54 ± 1.23

2.68 ± 0.98

0.001

FLIPI

0.165

 Low (0–1)

5 (9%)

43 (26.7%)

 Intermediate (2)

8 (36.3%)

64 (39.7%)

 High (≥ 3)

9 (40.9%)

54 (33.5%)

FLIPI2

0.059

 Low (0–1)

13 (56.5%)

105 (65.2%)

 Intermediate (2)

6 (26%)

39 (24.2%)

 High (≥ 3)

4 (17.4%)

17 (10.5%)

Pathologic grade

0.000

 Low (1–2)

24 (80%)

67 (35.4%)

 High (3a)

6 (20%)

122 (64.5%)