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Table 2 The Cox proportional hazard regression of clinical parameters for HT

From: Significance of initial, interim and end-of-therapy 18F-FDG PET/CT for predicting transformation risk in follicular lymphoma

  Univariate Cox regression Multivariate Cox regression
HR 95%CI P-value HR 95%CI P-value
Age, year 1.037 1.005–1.071 0.024 1.002 0.964–1.040 0.921
ECOG 1.720 0.940–3.148 0.079    
LDH, U/L 1.001 0.999–1.003 0.080    
Bone marrow involvement 1.304 0.604–2.813 0.499    
Area of enlarged lymph nodes (≥ 4) 0.843 0.405–1.754 0.648    
HGB, g/L 0.992 0.973–1.013 0.491    
Fibrinogen, g/L 1.612 1.206–2.154 0.001 1.385 1.002–1.915 0.048
FLIPI 1.253 0.878–1.788 0.212    
FLIPI2 1.557 1.058–2.291 0.025 1.550 1.002–2.398 0.049
Pathologic grade (grade 3a) 6.034 2.466–14.766 0.000 4.561 1.604–12.96 0.004