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Table 2 The significant changes of CXC chemokines expression in transcription level between different types of CC

From: Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment

TLR Type Fold change p-value t-test References
CXCL1 High-grade cervical squamous intraepithelial neoplasia epithelia vs. normal 7.048 2.83e−5 6.446 Zhai Cervix Statistics [27]
  Cervical squamous cell carcinoma epithelia vs. normal 4.462 1.33e−6 5.866 Zhai Cervix Statistics [27]
  Cervical squamous cell carcinoma vs. normal 3.895 5.62e−5 4.166 Scotto Cervix 2 Statistics [28]
CXCL3 High-grade cervical squamous intraepithelial neoplasia epithelia vs. normal 2.797 6.20e−4 4.111 Zhai Cervix Statistics [27]
CXCL5 High-grade cervical squamous intraepithelial neoplasia epithelia vs. normal 5.994 0.002 4.393 Zhai Cervix Statistics [27]
CXCL6 High-grade cervical squamous intraepithelial neoplasia epithelia vs. normal 2.976 0.003 3.969 Zhai Cervix Statistics [27]
CXCL8 Cervical squamous cell carcinoma vs. normal 13.807 5.04e−9 6.765 Scotto Cervix 2 Statistics [28]
  Cervical squamous cell carcinoma vs. normal 3.974 8.10e−8 7.474 Biewenga Cervix Statistics [29]
  Cervical squamous cell carcinoma epithelia vs. normal 3.789 8.81e−5 4.318 Zhai Cervix Statistics [27]
CXCL9 Cervical squamous cell carcinoma vs. normal 8.529 8.45e−9 11.614 Biewenga Cervix Statistics [29]
  Cervical squamous cell carcinoma vs. normal 3.523 1.47e−6 5.246 Scotto Cervix 2 Statistics [28]
CXCL10 Cervical squamous cell carcinoma vs. normal 3.982 4.89e−11 11.782 Biewenga Cervix Statistics [29]
  Cervical squamous cell carcinoma vs. normal 3.050 1.15e−4 3.947 Scotto Cervix 2 Statistics [28]
CXCL11 Cervical squamous cell carcinoma vs. normal 3.700 4.13e−16 12.455 Biewenga Cervix Statistics [29]
  Cervical squamous cell carcinoma vs. normal 3.555 2.09e−5 4.476 Scotto Cervix 2 Statistics [28]
CXCL13 Cervical squamous cell carcinoma vs. normal 19.655 9.32e−11 7.981 Scotto Cervix 2 Statistics [28]
  Cervical squamous cell carcinoma epithelia vs. normal 5.835 3.49e−5 4.636 Zhai Cervix Statistics [27]