Fig. 8

CBX2-knockdown inhibits CRC cell proliferation and invasion. a CBX2-knockdown suppressed cell proliferation, as determined by colony formation assays in HCT116 and HT29 cell lines (n = 3 independent experiments *P < 0.01). Scale bar, 100 magnification. b Apoptosis ratios of CBX2 in stably-transduced sh-Ctrl and sh-CBX2 HCT116 and HT29 cell lines were detected by flow cytometric analysis (n = 3 independent experiments *P < 0.025, **P < 0.01). c Knockdown of CBX2 significantly inhibited cell invasion in HCT116 and HT29 cell lines (n = 3 independent experiments, **P < 0.01)