circRNA | Role/Function | Regulation | Sample | References |
---|---|---|---|---|
circKLDHC10 | Biomarker | ↑ | Serum exosome | [19] |
hsa_circ_0004771 | Biomarker | ↑ | Cell line; seum exosome | [38] |
hsa_circ_0101802 | Biomarker | ↑ | Serum exosome | [39] |
hsa_circ_0000338 | Drug resistance | ↑ | Cell line; serum exosome | [42] |
circ_0032883 | Drug resistance | ↑ | Cell line exosome | [42] |
circ_0066629 | Drug resistance | ↑ | Cell line exosome | [42] |
ciRS-122 | Drug resistance | ↑ | Cell line exosome | [43] |
circ-FBXW7 | Drug resistance | ↓ | Cell line; serum exosome | [44] |
circ-PACRGL | Enhanced proliferation and invasion of cancer cells via miR-142-3p/miR-506-3p sponge to support the expression of TGF-β1 | ↑ | Cell line exosome | [45] |
circ-133 | Biomarker/enhanced metastasis via miR-133a/GEF-H1/RhoA axis | ↑ | Serum exosome | [46] |
hsa_circ_0008558 | Enhanced metastasis via modifying the maturation and allocation of miR-17 | ↑ | Cell line exosome | [47] |
circ_IFT80 | Enhanced proliferation and inhibited radiosensitivity by regulating miR-296-5p/MSI1 axis | ↑ | Cell line; serum exosome | |
hsa_circ_0000677 | Biomarker/enhanced metastasis and stemness properties possibly by upregulation of circ_0000677 via Wnt pathway | ↑ | Cell line exosome | [50] |
circFAT1and circRTN4 | Downregulation of circFAT1 and circRTN4 in mutant cells, suggesting a potential involvement of circRNAs in oncogenesis via increased exporting of the circRNAs to exosomes | ↑ | KRAS mutant cell line exosome | [51] |