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Fig. 2 | Cancer Cell International

Fig. 2

From: The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis

Fig. 2

Silencing of METTL3 can inhibit EMT, migration and invasion in BC by repressing MALAT1 expression. A The expression of METTL3 protein was detected by Western blot analysis. B The MALAT1 expression was detected by qRT-PCR. C The EMT-related proteins expression levels in cells were detected by Western blot analysis D The migration in cells examined by Transwell assay. E The invasion in cells examined by Transwell assay. *Significant difference (P < 0.05). The above data were all measurement data and expressed as mean ± standard deviation. One-way ANOVA with Tukey’s post-test was used for data comparison among multiple groups. All experiments were repeated three times

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