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Fig. 6 | Cancer Cell International

Fig. 6

From: The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis

Fig. 6

METTL3 increases tumorigenesis in BC cells by controlling HMGA2. A The growth curve of volume of transplanted tumor in each group. B The weight of transplanted tumor in each group. C The MALAT1 and miR-26b expression detected by qRT-PCR. D The expression of METTL3 and HMGA2 was detected by Western blot analysis. E The tumor nodules in the lung tissue of nude mice detected by HE staining (scale bar = 0.5 mm). *Significant difference (P < 0.05). The above data were all measurement data, expressed as mean ± standard deviation. One-way ANOVA with Tukey’s post-test was applied to data comparison among multiple groups. Repeated measurement analysis with Bonferroni post-test was used to analyze the data of each group at different time points, n = 6

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Cancer Cell International

ISSN: 1475-2867

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