Variables | Clinical stage I/II | Clinical stage III/IV | |||||
---|---|---|---|---|---|---|---|
Controls (N = 227) | Cancer (N = 60) | *OR (95% CI) | P | Cancer (N = 144) | AOR (95% CI) | P | |
rs2929973 | |||||||
Co-dominant TT | 102 (44.9) | 26 (43.3) | 1.00ref | 74 (51.4) | 1.00ref | ||
TG | 91 (40.1) | 28 (46.7) | 1.30 (0.46–3.70) | 0.624 | 57 (39.6) | 0.88 (0.54–1.42) | 0.591 |
GG | 34 (15.0) | 6 (10.0) | 1.71 (0.60–4.85) | 0.315 | 13 (9.0) | 0.58 (0.28–1.21) | 0.144 |
Dominant TT | 102 (44.9) | 26 (43.3) | 1.00ref | 74 (51.4) | 1.00ref | ||
TG + GG | 125 (55.1) | 34 (56.7) | 1.17 (0.62–2.20) | 0.636 | 70 (48.6) | 0.78 (0.50–1.23) | 0.286 |
Recessive TT + TG | 193 (85.0) | 54 (90.0) | 1.00ref | 131 (91.0) | 1.00ref | ||
GG | 34 (15.0) | 6 (10.0) | 0.67 (0.25–1.81) | 0.433 | 13 (9.0) | 0.61 (0.30–1.23) | 0.163 |
rs7843546 | |||||||
Co-dominant CC | 36 (15.9) | 17 (28.3) | 1.00ref | 24 (16.7) | 1.00ref | ||
CT | 119 (52.4) | 30 (50.0) | 0.54 (0.25–1.17) | 0.116 | 79 (54.9) | 1.08 (0.58–2.02) | 0.808 |
TT | 72 (31.7) | 13 (21.7) | 0.34 (0.14–0.84) | 0.020* | 41 (28.5) | 0.90 (0.46–1.77) | 0.756 |
Dominant CC | 36 (15.9) | 17 (28.3) | 1.00ref | 24 (16.7) | 1.00ref | ||
CT + TT | 191 (84.1) | 43 (71.7) | 0.46 (0.22–0.96) | 0.038* | 120 (83.3) | 1.02 (0.56–1.85) | 0.953 |
Recessive CT + CC | 155 (68.3) | 47 (78.3) | 1.00ref | 103 (71.5) | 1.00ref | ||
TT | 72 (31.7) | 13 (21.7) | 0.52 (0.25–1.10) | 0.087 | 41 (28.5) | 0.87 (0.54–1.41) | 0.569 |
rs10956697 | |||||||
Co-dominant CC | 86 (37.9) | 26 (43.3) | 1.00ref | 69 (47.9) | 1.00ref | ||
AC | 114 (50.2) | 27 (45.0) | 0.84 (0.43–1.63) | 0.609 | 61 (42.4) | 0.72 (0.45–1.16) | 0.176 |
AA | 27 (11.9) | 7 (11.7) | 1.08 (0.38–3.03) | 0.888 | 14 (9.7) | 0.83 (0.39–1.79) | 0.636 |
Dominant CC | 86 (37.9) | 26 (43.3) | 1.00ref | 69 (47.9) | 1.00ref | ||
AC + AA | 141 (62.1) | 34 (56.7) | 0.88 (0.47–1.66) | 0.696 | 75 (52.1) | 0.73 (0.46–1.14) | 0.166 |
Recessive CC + AC | 200(88.1) | 53 (88.3) | 1.00ref | 130 (90.3) | 1.00ref | ||
AA | 27 (11.9) | 7 (11.7) | 1.18 (0.45–3.13) | 0.739 | 14 (9.7) | 0.97 (0.47–2.01) | 0.943 |