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Table 4 Distribution frequency of WISP1polymorphisms in controls and gastric cancer patients stratified by ethnicity

From: Association between WNT-1-inducible signaling pathway protein-1 (WISP1) genetic polymorphisms and the risk of gastric cancer in Guangxi Chinese

Variables

Han

Zhuang

Cancer (N = 99)

Controls (N = 112)

OR (95% CI)

P

Cancer (N = 92)

Controls (N = 100)

OR (95% CI)

P

rs2929973

 

 Co-dominant TT

50

56

1.00ref

 

45

40

1.00ref

 

 TG

38

40

1.19(0.62–2.29)

0.601

40

42

0.90(0.46–1.74)

0.750

 GG

11

16

0.93(0.37–2.36)

0.875

7

18

0.36(0.13–1.02)

0.054

 Dominant TT

50

56

1.00ref

 

45

40

1.00ref

 

 TG + GG

49

56

1.08(0.59–1.96)

0.801

47

60

0.73(0.39–1.36)

0.324

 Recessive TT + TG

88

96

1.00ref

 

85

82

1.00ref

 

 GG

11

16

0.85(0.35–2.06)

0.714

7

18

0.38(0.14–1.02)

0.055

rs7843546

 Co-dominant CC

23

14

1.00ref

 

15

17

1.00ref

 

 CT

50

61

0.33(0.14–0.78)

0.012*

52

51

1.53(0.64–3.64)

0.335

 TT

26

37

0.29(0.11–0.76)

0.012*

25

32

0.94(0.37–2.38)

0.896

 Dominant CC

23

14

1.00ref

 

15

17

1.00ref

 

 CT + TT

76

98

0.32(0.14–0.74)

0.007*

77

83

1.27(0.56–2.87)

0.570

 Recessive CT + CC

73

75

1.00ref

 

67

68

1.00ref

 

 TT

26

37

0.73(0.37–1.41)

0.348

25

32

0.69(0.35–1.36)

0.285

rs10956697

 Co-dominant CC

48

41

1.00ref

 

41

36

1.00ref

 

 AC

38

58

0.71(0.37–1.36)

0.308

44

50

0.82(0.43–1.56)

0.542

 AA

13

13

1.23(0.47–3.23)

0.678

7

14

0.52(0.18–1.56)

0.246

 Dominant CC

48

41

1.00ref

 

41

36

1.00ref

 

 AC + AA

51

71

0.78(0.42–1.42)

0.412

51

64

0.76(0.41–1.42)

0.385

 Recessive CC + AC

86

99

1.00ref

 

85

86

1.00ref

 

 AA

13

13

1.42(0.57–3.51)

0.449

7

14

0.59(0.21–1.65)

0.310

  1. ref reference; AOR Adjusted odds ratio; 95% CI 95% confidence interval; adjusted for gender, age, BMI smoking and drinking alcohol; * P < 0.05 as statically significant