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Table 4 The remarkably enriched GO terms for these DEGs

From: Plastin-3 is a diagnostic and prognostic marker for pancreatic adenocarcinoma and distinguishes from diffuse large B-cell lymphoma

Ontology

ID

Description

Counta

adj. P

Gene ID

CC

GO:0005911

Cell–cell junction

12

6.95E−05

PERP/PPL/EPCAM/FAT1/CLDN1/BAIAP2L1/DSG2/CLDN7/CLDN12/PTPRK/CGN/PDLIM3

MF

GO:0050839

Cell adhesion molecule binding

11

0.002369034

SFRP2/PPL/SPP1/EPCAM/OLFM4/BAIAP2L1/TSPAN8/DSG2/CCN2/PROM1/CGN

CC

GO:0045177

Apical part of cell

9

0.002472218

EPCAM/FAT1/CLDN1/MYO6/MUC1/DSG2/KCNK1/PROM1/MAL2

CC

GO:0016324

Apical plasma membrane

8

0.002817074

EPCAM/FAT1/CLDN1/MUC1/DSG2/KCNK1/PROM1/MAL2

CC

GO:0016328

Lateral plasma membrane

4

0.003551437

EPCAM/CLDN1/DSG2/CLDN12

CC

GO:0030057

Desmosome

3

0.004170446

PERP/PPL/DSG2

CC

GO:0005923

Bicellular tight junction

5

0.004170446

EPCAM/CLDN1/CLDN7/CLDN12/CGN

CC

GO:0070160

Tight junction

5

0.004305753

EPCAM/CLDN1/CLDN7/CLDN12/CGN

BP

GO:0030198

Extracellular matrix organization

10

0.006175832

MMP7/SFRP2/SOX9/SPP1/PLOD2/MFAP2/ELF3/CCN2/SPINT2/CCDC80

CC

GO:0043296

Apical junction complex

5

0.006294613

EPCAM/CLDN1/CLDN7/CLDN12/CGN

BP

GO:0043062

Extracellular structure organization

10

0.010219773

MMP7/SFRP2/SOX9/SPP1/PLOD2/MFAP2/ELF3/CCN2/SPINT2/CCDC80

BP

GO:0098742

Cell–cell adhesion via plasma-membrane adhesion molecules

8

0.011695026

ANXA3/EPCAM/FAT1/CLDN1/DSG2/CLDN7/CLDN12/PCDHB16

CC

GO:0005884

Actin filament

4

0.020148378

PLS3/MYO6/PLS1/PDLIM3

MF

GO:0001968

Fibronectin binding

3

0.023328786

SFRP2/CCN2/CCDC80

CC

GO:0062023

Collagen-containing extracellular matrix

7

0.023568462

SFRP2/LGALS4/ASPN/MFAP2/CCN2/F3/CCDC80

MF

GO:0003779

Actin binding

8

0.042702752

PLS3/BAIAP2L1/MYO6/PLS1/ENC1/CGN/MLPH/PDLIM3

MF

GO:0002162

Dystroglycan binding

2

0.044071511

AGR2/AGR3

BP

GO:0016338

Calcium-independent cell–cell adhesion via plasma membrane cell-adhesion molecules

3

0.047603714

CLDN1/CLDN7/CLDN12

  1. BP biological processes, CC cellular component, MF molecular functions
  2. aThe “Count” refers to the numbers of DEGs that were enriched in the corresponding functional category