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Fig. 3 | Cancer Cell International

Fig. 3

From: [6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling

Fig. 3

Inhibition of 6-Paradol on migration and invasion of pancreatic cancer cells. A–D Transwell assays were performed to evaluate the migration and invasion abilities of pancreatic cancer cells and the cells were treated with different concentrations of 6-Paradol (0, 20, 40, 80 μM). Migration abilities were evaluated without Matrigel (A) and invasion abilities were evaluated with Matrigel (B) (scale bar: 100 μm). The statistical chart of migration cells (C) and invasion cells (D) in different concentrations of 6-Paradol. E–G Wound healing assays were performed to further measure the migrated abilities in MIA PaCa-2 and SW1990 (scale bar: 400 μm). H, I Western blot assays were used to analyze the effect of 6-Paradol on EMT. *p < 0.05, **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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