Table 2 Multivariate survival analyses of factors contributing to OS in Chinese HNSCC patients were performed using the Cox proportional hazards regression model
From: NAT10 as a potential prognostic biomarker and therapeutic target for HNSCC
| Clinical-pathological parameters | Patients (n = 267) | MST (days) | HR (95% CI) | P value |
|---|---|---|---|---|
| NAT10 IHC | 0.012 | |||
| Low | 83 | 1872 | Reference | |
| High | 156 | 1378 | 1.564 (1.105–2.213) | |
| Negative | 28 | 1419 | ||
| Age | 2.94E−05 | |||
| < 65 | 206 | 1738 | Reference | |
| ≥ 65 | 61 | 510 | 2.399 (1.591–3.616) | |
| Stage | 0.068 | |||
| I&II | 172 | 1685 | Reference | |
| III&IV | 95 | 1177 | 1.435 (0.974–2.114) | |
| HPV | 0.125 | |||
| Positive | 22 | 1664 | Reference | |
| Negative | 245 | 1569 | 2.475 (0.776–7.874) | |
| Type | 0.005 | |||
| Primary | 219 | 1625 | Reference | |
| Recurrent | 48 | 511 | 1.898 (1.211–2.974) | |