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Fig. 4 | Cancer Cell International

Fig. 4

From: TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer

Fig. 4

A In TCGA-PRAD, TACR2 was enriched in adherent junctions, regulation of actin cytoskeleton, regulation of autophagy, and the Wnt signaling pathway. B Biology process analysis of TACR2 in TCGA-PRAD. C Correlation between TACR2 and important related genes in the Wnt pathway. TACR2 negatively correlated with FZD6 (P < 0.001; COR = − 0.25), GSK3B (P < 0.001; COR = − 0.24) and MAPK8 (P < 0.001; COR = − 0.26). TACR2 positively correlated with PRKACA (P < 0.001; COR = 0.30), PRKCA (P < 0.001; COR = 0.33) and PRKCB (P < 0.001; COR = 0.40), Wnt2B (P < 0.001; COR = 0.26), and Wnt5B (P < 0.001; COR = 0.45)

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Cancer Cell International

ISSN: 1475-2867

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