Fig. 3

DDX52 knockdown inhibits PCa xenograft growth. a The mice were killed at 6 weeks after implanting 22RV1 cells, and the volumes of the xenograft tumors are shown. b Weights of the xenograft tumors in the control and treated groups (Mann–Whitney test, n = 7, error bars represent standard deviations; ***p < 0.001). c Kaplan–Meier plot showing the time of xenograft genesis after implantation (log-rank test; ***p < 0.001). d Examples of tumor xenografts that underwent hematoxylin and eosin (HE) staining and DDX52 and Ki67 immunohistochemical staining (scale bar: 100 μm). e, f The positive cells in random areas in each xenograft section were counted. e DDX52 expression was measured according to the IHC score (Mann–Whitney test, error bars represent standard deviations; **p < 0.01). f Ki67 expression was measured according to the number of positively stained cells (Mann–Whitney test, error bars represent standard deviations; **p < 0.01)