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Table 1 Association between LYRM4 mRNA expression and various clinicopathological factors of HBV-related LIHC patients

From: Iron-sulphur cluster biogenesis factor LYRM4 is a novel prognostic biomarker associated with immune infiltrates in hepatocellular carcinoma

Variables LYRM4 mRNA expression p value Multivariate analysisa
Low (n = 79) High (n = 78) OR 95% p value
Age, years
 ≤ 54 48 37 0.09 1 Reference  
 > 54 31 41   1.570 0.749–3.288 0.232
Gender
 Male 62 65 0.44 1 Reference  
 Female 17 13   0.700 0.271–1.806 0.461
Preoperative AFP (ng/ml)
 ≤ 200 38 49 0.06 1 Reference  
 > 200 40 28   0.675 0.312–1.461 0.318
TB (µmol/L)
 ≤ 20 77 73 0.43 1 Reference  
 > 20 2 5   2.995 0.457–19.63 0.253
ALT (U/L)
 ≤ 50 50 60 0.91 1 Reference  
 > 50 29 36   0.405 0.170–0.968 0.042
γ-GT (U/L)
 ≤ 60 41 40 1.00 1 Reference  
 > 60 38 37   1.957 0.830–4.615 0.125
HBcAb
 No 5 4 0.98 1 Reference  
 Yes 74 74   1.779 0.356–8.877 0.483
Tumor size (cm)
 ≤ 5 39 36 0.69 1 Reference  
 > 5 40 42   1.382 0.612–3.124 0.436
Tumor number
 Single 58 58 0.89 1 Reference  
 Multiple 21 20   1.226 0.523–2.871 0.639
Tumor thrombus
 No 55 66 0.03 1 Reference  
 Yes 24 12   0.355 0.132–0.957 0.041
Tumor encapsulation
 No 27 17 0.08 1 Reference  
 Yes 50 59   2.345 1.035–5.315 0.041
Tumor differentiation
 High 37 45 0.15 1 Reference  
 Low 42 32   0.771 0.368–1.618 0.492
History of liver cirrhosis
 No 19 27 0.15 1 Reference  
 Yes 60 51   0.519 0.223–1.212 0.130
  1. Pearson Chi-Square test was used to analyze the relationship between LYRM4 mRNA expression and clinicopathological characteristics. Font bold means have statistical significance p < 0.05
  2. aLogistics regression was used to multivariate analysis