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Fig. 7 | Cancer Cell International

Fig. 7

From: Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Fig. 7

Lnc-Ma301 inhibits the proliferation and migration of HCC cells via interaction with caprin-1 in vitro. A The expression of caprin-1 in different cell lines (left). Confirmation of the effects of caprin-1 silencing (si) (middle) and overexpression (OE) (right). B The CCK8 assay was used to confirm the effect of lnc-Ma301 and caprin-1 interaction on cell proliferation. C A transwell assay was used to determine the effect of lnc-Ma301 and caprin-1 interaction on cell migration. D The expression of EMT-associated genes vimentin, E-cadherin, and slug were analyzed by qRT-PCR. E Levels of EMT-associated proteins vimentin, E-cadherin, and slug were analyzed by western blotting. Data are presented as mean ± standard error of the mean (SEM). *P < 0.05

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