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Table 1 Relationship of lncMa-301 expression and overall survival with demographic and clinical data in HCC patients

From: Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Variable lncMa-301 expression Overall survival analysis
Low (n = 108) High (n = 108) Odds ratio (95%CI) P No. of patients Hazard ratio (95%CI) P
Sex
 Female 13 16 0.79 (0.36–1.73) 0.549 29 Ref. 0.184
 Male 95 92 Ref. 187 2.00 (0.72–5.57)
Age, year
 < 60 84 90 0.70 (0.36–1.38) 0.302 174 Ref. 0.144
 ≥ 60 24 18 Ref.   42 0.53 (0.23–1.24)  
Size, cm
 < 5 29 35 0.77 (0.43–1.38) 0.371 64 Ref. 0.016
 ≥ 5 79 73 Ref.   152 2.67 (1.20–5.95)  
Number of tumors
 < 3 97 99 0.80 (0.32–20.2) 0.639 196 Ref. 0.023
 ≥ 3 11 9 Ref.   20 2.42 (1.13–5.17)  
Tumor capsule
 Complete 59 65 0.80 (0.46–1.37) 0.409 124 Ref. 0.015
 Incomplete/absent 49 43 Ref.   92 2.03 (1.15–3.58)  
Lymph node metastasis
 No 99 104 0.42 (0.13–1.42) 0.153 203 Ref. 0.006
 Yes 9 4 Ref.   13 3.06 (1.37–6.81)  
Macrovascular invasion
 No 66 69 0.89 (0.51–1.54) 0.673 135 Ref.  < 0.001
 Yes 42 39 Ref.   81 2.92 (1.65–5.16)  
Microvascular invasion
 No 42 45 0.89 (0.52–1.54) 0.677 87 Ref.  < 0.001
 Yes 66 63 Ref.   129 4.04 (1.89–8.62)  
AFP, ng/mL
 < 400 53 55 0.93 (0.55–1.58) 0.785 108 Ref. 0.181
 ≥ 400 55 53 Ref.   108 1.47 (0.84–2.59)  
BCLC stage
 0/A 47 51 0.86 (0.50–1.47) 0.585 98 Ref. 0.001
 B/C 61 57 Ref.   118 2.94 (1.53–5.65)  
EST031.1 expression
 Low 108 0   NA 108 Ref. 0.036
 High 0 108    108 0.54 (0.30–0.96)  
  1. Bold values indicate P value less than 0.05
  2. AFP alpha fetoprotein, BCLC Bacelona Clinic Liver Cancer, CI confidence interval, HCC hepatocellular carcinoma, Ref. reference