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Table 1 Relationship of lncMa-301 expression and overall survival with demographic and clinical data in HCC patients

From: Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Variable

lncMa-301 expression

Overall survival analysis

Low (n = 108)

High (n = 108)

Odds ratio (95%CI)

P

No. of patients

Hazard ratio (95%CI)

P

Sex

 Female

13

16

0.79 (0.36–1.73)

0.549

29

Ref.

0.184

 Male

95

92

Ref.

187

2.00 (0.72–5.57)

Age, year

 < 60

84

90

0.70 (0.36–1.38)

0.302

174

Ref.

0.144

 ≥ 60

24

18

Ref.

 

42

0.53 (0.23–1.24)

 

Size, cm

 < 5

29

35

0.77 (0.43–1.38)

0.371

64

Ref.

0.016

 ≥ 5

79

73

Ref.

 

152

2.67 (1.20–5.95)

 

Number of tumors

 < 3

97

99

0.80 (0.32–20.2)

0.639

196

Ref.

0.023

 ≥ 3

11

9

Ref.

 

20

2.42 (1.13–5.17)

 

Tumor capsule

 Complete

59

65

0.80 (0.46–1.37)

0.409

124

Ref.

0.015

 Incomplete/absent

49

43

Ref.

 

92

2.03 (1.15–3.58)

 

Lymph node metastasis

 No

99

104

0.42 (0.13–1.42)

0.153

203

Ref.

0.006

 Yes

9

4

Ref.

 

13

3.06 (1.37–6.81)

 

Macrovascular invasion

 No

66

69

0.89 (0.51–1.54)

0.673

135

Ref.

 < 0.001

 Yes

42

39

Ref.

 

81

2.92 (1.65–5.16)

 

Microvascular invasion

 No

42

45

0.89 (0.52–1.54)

0.677

87

Ref.

 < 0.001

 Yes

66

63

Ref.

 

129

4.04 (1.89–8.62)

 

AFP, ng/mL

 < 400

53

55

0.93 (0.55–1.58)

0.785

108

Ref.

0.181

 ≥ 400

55

53

Ref.

 

108

1.47 (0.84–2.59)

 

BCLC stage

 0/A

47

51

0.86 (0.50–1.47)

0.585

98

Ref.

0.001

 B/C

61

57

Ref.

 

118

2.94 (1.53–5.65)

 

EST031.1 expression

 Low

108

0

 

NA

108

Ref.

0.036

 High

0

108

  

108

0.54 (0.30–0.96)

 
  1. Bold values indicate P value less than 0.05
  2. AFP alpha fetoprotein, BCLC Bacelona Clinic Liver Cancer, CI confidence interval, HCC hepatocellular carcinoma, Ref. reference