Fig. 5
From: Ultrastructural analysis of breast cancer patient-derived organoids
Analysis of mitochondria morphology. a Representative image of round mitochondria with few and peripherical ridges observed in PDO from healthy tissue. b PDO from invasive ductal carcinoma (IDC) evidenced long mitochondria with well represented ridges. c Elongated and rich-in ridges mitochondria observed in PDO derived from ductal in situ carcinoma (DCIS). d Representative image of elongated mitochondria identified in a PDO from invasive lobular carcinoma (ILC). M = mitochondria; Ly = lysosomes; G = Golgi apparatus; *= intracellular lumen; N = nucleus; D = desmosomes