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Fig. 1 | Cancer Cell International

Fig. 1

From: Ovarian cancer: epigenetics, drug resistance, and progression

Fig. 1

Epigenetic processes include DNA methylation, histone modification, non-coding RNA, RNA modification, chromatin remodeling, and genomic imprinting. a DNA methylation is divided into two categories: the hypermethylation of CpG islands and global hypomethylation. b Histone post-translational modifications, including methylation, acetylation, phosphorylation, deamination, ubiquitination, ADPÔÇÉribosylation and proline isomerization. c Non-coding RNA including miRNA, lncRNA, rRNA, tRNA, snRNA, snoRNA, sncRNA, siRNA, etc., act in the nucleus or cytoplasm. d Post-transcriptional modification of RNA through RNA editing and RNA methylation. e Chromatin-remodeling complexes are grouped into four major families: SWI/SNF, INO80, ISWI, and CHD. f Genomic imprinting is an epigenetic process that mainly includes maternal imprinting and paternal imprinting

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