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Table 1 Molecular targets of miR-132 during tumor progressions

From: Molecular mechanisms of the microRNA-132 during tumor progressions

Study Year Type Gene Target Samples MiR-132 function
Zhang et al. [23] 2014 Breast miR-132 HN1 10 NT*
NMuMG, 4T1, MDA-MB-231, and MCF10A cell lines
Tumor suppressor
Lian et al. [119] 2016 Laryngeal miR-132 FOXO1 10 NT
Hep-G2 and AMC-HN-8 cell lines
Oncogene
Han et al. [132] 2020 Retinoblastoma ILF3-AS1 miR-132 50 NT
Y79, HXO-RB44, SO-RB50, and RB1 cell lines
Tumor suppressor
Zhang et al. [129] 2020 Hepatocellular LINC00160 miR-132 68 NT
HCCLM3, Huh7, Hep3B, and MHCC97 cell lines
Tumor suppressor
Zhang et al. [123] 2019 Pancreatic miR-132 PTEN 60 NT
PAN-1, KLM-1, and PaCa-2 cell lines
Oncogene
Renjie et al. [45] 2015 Pituitary miR-132 SOX5 16 T
MMQ and GH3 cell lines
Tumor suppressor
Xie et al. [124] 2018 Breast miR-132 PTEN 53 NT
MCF-7 cell line
Oncogene
Chen et al. [94] 2016 Glioma miR-132 TTK 46 T and 9 N
U87 cell line
Tumor suppressor
Song et al. [140] 2017 Colorectal XIST miR-132 50 NT
SW480, SW620, LOVO,HT29, and HCT116 cell lines
Tumor suppressor
Li et al. [68] 2016 Glioma miR-132 SIRT1 U251 and U87 cell lines Tumor suppressor
Zhao et al. [144] 2019 Pancreatic miR-132 SHH 23 T and 25 N
MiaPaCe-2a cell line
Oncogene
Zhang et al. [79] 2019 Ovarian miR-132 BMI1 SKOV3 Tumor suppressor
Xue et al. [43] 2020 Nasopharyngeal LINC01551 miR-132 24 NT
HNE1, SUNE2, HONE1, CNE2, and 6-10B cell lines
Tumor suppressor
Liu et al. [89] 2018 Colorectal MIAT miR-132 30 NT
Ht29, SW480, and LOVO cell lines
Tumor suppressor
Zhou et al. [51] 2018 Glioma NEAT1 miR-132 14 T and 5 N
U87, U251, SHG-44, and U-118MG cell lines
Tumor suppressor
Liu et al. [42] 2020 Pancreatic PTTG3P miR-132 60 NT
AsPc-1, BxPC-3, CaPAN-2, MiaPaCa-2, PANC-1, and SW1990 cell lines
Oncogene
Chen et al. [36] 2019 Thyroid miR-132 FOXA1 30 NT
TPC1 and GLAG-66 cell lines
Tumor suppressor
Tian et al. [64] 2016 Ovarian miR-132 E2F5 32 NT
SKOV3, OVCAR3, and A2780 cell lines
Tumor suppressor
Guo et al. [84] 2018 Lung miR-132 USP9X A549 and NCI-1299 cell lines Tumor suppressor
Wang et al. [35] 2018 Breast miR-132 FOXA1 30 NT
SK-BR3 and MDA-MB-468 cell lines
Tumor suppressor
Li et al. [128] 2019 Breast miR-132 LAPTM4B 131 T and 87 N
MCF-7, MCF-10A, ZR-75–1, T470, and MDA-MB-231 cell lines
Tumor suppressor
Lei et al. [147] 2015 Hepatocellular miR-132 YAP Huh7 and HepG2 cell lines Tumor suppressor
Liu et al. [49] 2019 Bladder CIRC-DOCK1 miR-132 23 T and 32 N
BIU-87, EJ-m3, T24, and 5673 cell lines
Tumor suppressor
Qu et al. [108] 2016 Prostate miR-132 GLUT1 PC-3 and DU-145 cell lines Tumor suppressor
Geng et al. [112] 2016 Astrocytoma miR-132 PEA15 U251 and U87 cell lines Tumor suppressor
Chen et al. [126] 2018 Thyroid miR-132 CSDE1 BCPAP, TPC1, and 8505c cell lines Tumor suppressor
Cheng et al. [90] 2017 Glioblastoma miR-132 TUSC3 U87MG Oncogene
Liu et al. [58] 2015 Osteosarcoma miR-132 SOX4 MG63, HOS, 143B, U2OS, and SaOS-2 cell lines Tumor suppressor
Abukiwan et al. [136] 2019 Pancreatic miR-132 TGFβ 35 NT
AsPC-1 and PANC-1 cell lines
Oncogene
Zhao et al. [130] 2015 Cervical miR-132 SMAD2 20 NT
HeLa and C33A cell lines
Tumor suppressor
Li et al. [61] 2015 Lung miR-132 SOX4 H460, A549, and YTMLC-9 cell lines Tumor suppressor
Chen et al. [133] 2020 Oral miR-132 TGFβ 37 NT
SCC-9 and CAL-27 cell lines
Tumor suppressor
Zhang et al. [70] 2019 Colorectal SNHG5 miR-132 25 NT
RKO, SW480, and LOVO cell lines
Tumor suppressor
Li et al. [30] 2015 Gastric miR-132 FOXO1 28 NT
AGS and SNU-5 cell lines
Oncogene
Lin et al. [74] 2016 Ovarian miR-132 CDH2, VIM SKOV3 and OV2008 cell lines Tumor suppressor
Liu et al. [139] 2019 Colorectal miR-132 ERK1 NCM460, LOVO, and SW480 cell lines Tumor suppressor
Liu et al. [102] 2017 Gastric miR-132 CD44, FN1 201 NT
BGC823, AGS, and HGC27 cell lines
Tumor suppressor
He et al. [107] 2017 Gastric miR-132 MUC13 40 NT
MKN28 cell line
Tumor suppressor
Huang et al. [62] 2020 Hepatocellular miR-132 SOX4 HepG2, Huh7, and HccLM3 cell lines Tumor suppressor
Liu et al. [78] 2017 Cervical miR-132 BMI1 104 NT
HeLa, SiHa, and C33A cell lines
Tumor suppressor
Zhang et al. [80] 2018 Lung SOX2OT miR-132 48 NT
A549, H1299, NCI-H460, and HCC-827 cell lines
Tumor suppressor
Wei et al. [131] 2019 Bladder miR-132 SMAD2 32 NT
T24 cell line
Tumor suppressor
He et al. [86] 2020 Colorectal SNHG16 miR-132 50 NT
SW480 and SW620 cell lines
Tumor suppressor
Fu et al. [60] 2016 Prostate miR-132 SOX4 57 NT
LnCap and VCap cell lines
Tumor suppressor
Zheng et al. [81] 2014 Colorectal miR-132 ZEB2 62 NT
HT29, LOVO, HTC116, SW480, and SW620 cell lines
Tumor suppressor
Wang et al. [113] 2014 Osteosarcoma miR-132 CCNE1 10 NT
HOS, MG63, 143B, and Saos-2 cell lines
Tumor suppressor
Li et al. [32] 2016 Nasopharyngeal miR-132 FOXA1 CNE2 Tumor suppressor
  1. * Tumor (T) tissues and Normal (N) margins