Knockdown lncRNA CRNDE enhances temozolomide chemosensitivity by regulating autophagy in glioblastoma

Table 1 Correlation of the CRNDE expression with clinical and pathological characteristics in tissue samples from glioma patients

Characteristics	CRNDE expression		Total (n = 58)	χ²	P value
Characteristics	Low (n = 23)	High (n = 35)	Total (n = 58)	χ²	P value
Age (years)
< 55	12	18	30	0.003	0.584
≥ 55	11	17	28
Gender
Male	13	21	34	0.069	0.502
Female	10	14	24
Location
Supratentorial	16	26	42	0.155	0.459
Subtentorial	7	9	16
Tumor size (mm)
< 50	15	13	28	4.381	0.034^*
≥ 50	8	22	30
Peritumoral edema range (mm)
< 10	10	6	16	4.819	0.030^*
≥ 10	13	29	42
Histological grade
Grade I–II	17	5	22	20.960	< 0.001^*
Grade III–IV	6	30	36
Postoperative recurrence
Yes	8	23	31	5.337	0.020^*
No	15	12	27

ISSN: 1475-2867