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Table 2 Univariate and multivariate Cox proportional hazards regression model analysis of factors related to overall survival for patients

From: Knockdown lncRNA CRNDE enhances temozolomide chemosensitivity by regulating autophagy in glioblastoma

Characteristics Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age (years)     
  < 55 vs. ≥ 55 0.947 0.628–1.298 0.683
Gender     
 Male vs. Female 0.752 0.451–1.364 0.464
Location    
 Supratentorial vs. Subtentorial 1.134 0.967–1.602 0.301
Tumor size (mm)     
 < 50 vs. ≥ 50 0.828 0.754–8.976 0.832
Peritumoral edema range (mm)     
 < 10 vs. ≥ 10 1.876 0.667–3.546 0.795
Histological grade     
 I + II vs. III + IV 0.392 0.265–0.769 0.024* 0.492 0.328–0.893 0.040*
Postoperative recurrence     
 No vs. Yes 0.487 0.291–0.896 0.039* 0.537 0.314–0.915 0.043*
CRNDE expression      
 High vs. Low 2.468 1.109–4.654 0.002* 1.897 1.132–2.387 0.006*
  1. *P < 0.05 was considered to be statically significant