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Fig. 5 | Cancer Cell International

Fig. 5

From: Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5

Fig. 5

SLC1A5 acted as a target for miR-107. A The binding sites between miR-107 and SLC1A5 were predicted by starbase. B–G Th combination between miR-107 and SLC1A5 was verified using the dual-luciferase reporter assay (B, C), RIP assay (D, E) and RNA pull-down assay (F, G). H The mRNA expression of SLC1A5 was measured via qRT-PCR in normal and EC tissues. I The linear relationship between miR-107 and SLC1A5 was analyzed via Pearson’s correlation coefficient. J, K The SLC1A5 protein expression was detected via western blot in EC tissues (J) and cells (K). L The regulation of SLC1A5 protein level by miR-107 overexpression or inhibition was examined via western blot. ***P < 0.001, ****P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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