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Fig. 1 | Cancer Cell International

Fig. 1

From: CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway

Fig. 1

CMTM3 was downregulated in chordoma tissues and inhibited the growth of chordoma cells. A The general research methodology of the entire study. B The expression of CMTM3 in tumor (T) and paired adjacent non-tumor (N) tissues was detected by western blot. C The expression of CMTM3 in chordoma cell lines was detected by Real-time PCR. Representative data was shown as the average number from one independent experiment. D The expression of CMTM3 in chordoma cell lines was detected by western blot. EH CCK-8 assays were performed in chordoma cells after CMTM3 overexpression or silencing. IL CFU assays of chordoma cells in CMTM3 overexpressed or silenced cells (IK: 1000 cells/well. L: 500 cells/well). Data are representative of three independent experiments and presented as the mean ± s.d (Scr: control siRNA, *p < 0.05, **p < 0.01, ***p < 0.001)

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