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Fig. 5 | Cancer Cell International

Fig. 5

From: Lymphocyte activating gene 3 protein expression in nasopharyngeal carcinoma is correlated with programmed cell death-1 and programmed cell death ligand-1, tumor-infiltrating lymphocytes

Fig. 5

The survival curves of LAG-3, PD-1, and PD-L1 on TILs, PDL1 on TCs layered by the cut-off values estimated by X-tile. A Disease-free survival (DFS) differed significantly between patients with LAG-3 expression on fewer than 14 cells and those with LAG-3 expression on more than 14 cells (P < 0.001). B DFS differed significantly between patients with PD-1 expression on fewer than two cells and those with PD-1 expression on more than two cells (P < 0.001). C DFS differed significantly between patients with PD-L1 on TCs with a score lower than nine and those with PD-L1 on TCs with a score higher than nine (P = 0.027). D DFS differed significantly between patients with PD-L1 expression on fewer than 1% of TILs and those with PD-L1 expression on more than 1% of TILs (P = 0.002). E DFS differed significantly between patients with lower LAG-3 and PD-L1 expression on TILs and those with higher LAG-3 and PD-L1 expression on TILs (P < 0.001). F DFS differed significantly between patients with lower LAG-3 and PD-1 expression and those with higher LAG-3 and PD-1 expression (P < 0.001). G DFS differed significantly between patients with lower LAG-3 and PD-L1 expression on TCs and those with higher LAG-3 and PD-L1 expression on TCs (P = 0.037)

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