Table 8 Clinical applications as of March 2021 for bispecific antibodies targeting LAG-3 expression
Antibody name | Targets | Clinical application acceptance number | Date |
|---|---|---|---|
HLX26 | LAG-3 | CXSL2100041 | 2021-02-03 |
IBI323 | PD-L1 × LAG-3 | CXSL2000242 | 2020-08-25 |
EMB-02 | PD-1 × LAG-3 | CXSL2100047 | 2020-05-23 |
DNV3 | LAG-3 | CXSL2000121 | 2020-05-22 |
KL-A289 | LAG-3 | CXSL2000108 | 2019-11-16 |
MGD013 | PD-1 × LAG-3 | JXSL1900114 | 2019-08-23 |
SHR-1802 | LAG-3 | CXSL1900090 | 2019-05-27 |
LBL-007 | LAG-3 | JXSL1900040 | 2019-04-26 |
IBI110 | LAG-3 | CXSL1900040 | 2019-04-26 |
EOC202 | LAG-3 | CTR20180185 | 2018-06-25 |