Description | Gene markers | SKCM | |||
---|---|---|---|---|---|
None | Purity | ||||
Cor | P | Cor | P | ||
CD8 + T cell | CD8A | − 0.012 | 0.794 | − 0.016 | 0.738 |
CD8B | − 0.022 | 0.636 | − 0.028 | 0.553 | |
B cell | CD19 | − 0.005 | 0.907 | − 0.011 | 0.810 |
CD79A | − 0.084 | 0.068 | − 0.086 | 0.066 | |
T cell (general) | CD3D | − 0.048 | 0.302 | − 0.053 | 0.254 |
CD3E | − 0.065 | 0.158 | − 0.069 | 0.140 | |
CD2 | − 0.029 | 0.523 | − 0.035 | 0.456 | |
Monocyte | CD86 | 0.094 | 0.042 | 0.094 | 0.044 |
CD14 | 0.028 | 0.547 | 0.038 | 0.421 | |
CD115(CSF1R) | 0.065 | 0.162 | 0.070 | 0.133 | |
TAM | CCL2 | 0.063 | 0.171 | 0.068 | 0.146 |
CD68 | 0.081 | 0.078 | 0.067 | 0.152 | |
IL10 | 0.165 |  < 0.001 | 0.167 |  < 0.001 | |
M1 Macrophage | INOS(NOS2) | − 0.015 | 0.743 | − 0.009 | 0.844 |
IRF5 | 0.020 | 0.671 | 0.027 | 0.571 | |
COX2(PTGS2) | 0.148 | 0.001 | 0.151 | 0.001 | |
CD40 | 0.019 | 0.676 | 0.025 | 0.594 | |
M2 Macrophage | CD206(MRC1) | 0.165 |  < 0.001 | 0.177 |  < 0.001 |
CD163 | 0.180 |  < 0.001 | 0.189 |  < 0.001 | |
VSIG4 | 0.099 | 0.031 | 0.109 | 0.020 | |
CD200R1 | 0.147 | 0.001 | 0.146 | 0.002 | |
MS4A4A | 0.130 | 0.005 | 0.135 | 0.004 | |
Natural killer cell | KIR3DL1 | − 0.055 | 0.230 | − 0.063 | 0.175 |
KIR3DL2 | − 0.080 | 0.083 | − 0.076 | 0.104 | |
KIR3DL3 | − 0.122 | 0.008 | − 0.125 | 0.008 | |
KIR2DS4 | − 0.122 | 0.008 | − 0.084 | 0.071 |