Table 2 Summary of studies on the molecular markers of ferroptosis related to the diagnosis, prognosis and staging of pancreatic cancer
From: Current understanding of ferroptosis in the progression and treatment of pancreatic cancer
Molecular marker | Biomolecule type | Clinical relevance | References |
|---|---|---|---|
Ferritin | Protein | Diagnosis, prognosis | |
Ferroportin | Protein | Diagnosis, prognosis | |
Hepcidin | Protein | Prognosis, TNM stage | [67] |
Lipocalin 2 | Protein | Diagnosis | |
TFR1 | Protein | Diagnosis, prognosis, TNM stage | |
SLC7A11 | DNA | Prognosis | [70] |
GPX4 | Protein | Prognosis | [67] |
ARF6 | Protein | Prognosis | [57] |
SLC25A37/28 | DNA | Prognosis | [71] |
PARK2 | DNA | Prognosis | [71] |
AIM2 | DNA | Prognosis | [71] |
NUPR1 | DNA | Prognosis | [73] |
LCN2 | DNA | Prognosis | [73] |
MGST1 | DNA | Prognosis | [56] |
PTGS2 | DNA | Prognosis | [72] |
MT1G | DNA | Prognosis | [72] |
TUBE1 | DNA | Prognosis | [72] |
ATG4D | DNA | Prognosis | [72] |