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Fig. 7 | Cancer Cell International

Fig. 7

From: RNA sequencing analysis reveals the competing endogenous RNAs interplay in resected hepatocellular carcinoma patients who received interferon-alpha therapy

Fig. 7

MARCH3 expression correlates with TICCs in HCC. a t-SNE projection depicting cellular composition of human HCC tumors. Cells that share similar transcriptome profiles were grouped by colors and were annotated using lineage specific markers. b, c t-SNE plot depicting MARCH3 in the cells including B cells, CD8 + T cells, endothelial cells, fibroblast cells, hepatic progenitor cells, malignant cells, macrophage cells and plasma cells. d Correlation between MARCH3 expression with tumor associated immune cells in HCC. e Correlation between MARCH3 alternations (arm-level deletion, diploid/normal, arm level gain and high amplication) and the infiltrating levels of immune cells. f, g Correlation between MARCH3 expression and the gene markers of M1 macrophages (COX2 and IRF5) and M2 macrophages (cd163, VSIG4 and MA4A4A) in HCC

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