Skip to main content

Table 1 Baseline characteristics and analysis of prognostic factors for LRFS in 126 patients

From: Dysfunction of apoptosis and autophagy correlates with local recurrence in esophageal squamous cell carcinoma after definitive chemoradiation

Factor

Number

(%)

Median

(months)

1-year

LRFS (%)

3-year

LRFS (%)

HR

95% CI

P

Sex

 Male

90 (71.4)

13.7

58.9

20.0

1.23

0.83 to 1.83

0.296

 Female

36 (28.6)

10.6

47.2

19.4

   

Age at diagnosis (years)

 < 60

58 (46.0)

15.5

67.2

22.4

1.33

0.94 to 1.90

0.108

 ≥ 60

68 (54.0)

10.6

45.6

17.6

   

Tumor location

 Upper thoracic

53 (42.1)

13.0

54.7

22.6

1.12

0.87 to 1.46

0.515

 Middle thoracic

55 (43.6)

14.0

56.4

21.8

   

 Lower thoracic

18 (14.3)

9.0

50.0

16.7

   

Differentiation

 Well

29 (23.0)

13.7

65.5

20.7

0.97

0.76 to 1.25

0.677

 Moderate

68 (54.0)

12.5

51.7

27.6

   

 Poor

29 (23.0)

12.1

51.5

16.2

   

T stage

 T2

58 (46.0)

15.5

67.2

29.3

1.45

1.14 to 1.85

0.007

 T3

46 (36.5)

10.1

43.5

15.2

   

 T4

22 (17.5)

10.5

45.5

13.6

   

Lymph nodes

 Negative

46 (36.5)

13.0

58.7

21.7

1.14

0.79 to 1.64

0.493

 Positive

80 (63.5)

12.5

52.5

18.8

   

7th AJCC stage

 II

60 (47.6)

19.0

63.3

31.1

1.85

1.27 to 2.69

0.001

 III

66 (52.4)

10.6

47.0

10.6

   
  1. LRFS local recurrence-free survival, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer