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Table 1 Baseline characteristics and analysis of prognostic factors for LRFS in 126 patients

From: Dysfunction of apoptosis and autophagy correlates with local recurrence in esophageal squamous cell carcinoma after definitive chemoradiation

Factor Number
(%)
Median
(months)
1-year
LRFS (%)
3-year
LRFS (%)
HR 95% CI P
Sex
 Male 90 (71.4) 13.7 58.9 20.0 1.23 0.83 to 1.83 0.296
 Female 36 (28.6) 10.6 47.2 19.4    
Age at diagnosis (years)
 < 60 58 (46.0) 15.5 67.2 22.4 1.33 0.94 to 1.90 0.108
 ≥ 60 68 (54.0) 10.6 45.6 17.6    
Tumor location
 Upper thoracic 53 (42.1) 13.0 54.7 22.6 1.12 0.87 to 1.46 0.515
 Middle thoracic 55 (43.6) 14.0 56.4 21.8    
 Lower thoracic 18 (14.3) 9.0 50.0 16.7    
Differentiation
 Well 29 (23.0) 13.7 65.5 20.7 0.97 0.76 to 1.25 0.677
 Moderate 68 (54.0) 12.5 51.7 27.6    
 Poor 29 (23.0) 12.1 51.5 16.2    
T stage
 T2 58 (46.0) 15.5 67.2 29.3 1.45 1.14 to 1.85 0.007
 T3 46 (36.5) 10.1 43.5 15.2    
 T4 22 (17.5) 10.5 45.5 13.6    
Lymph nodes
 Negative 46 (36.5) 13.0 58.7 21.7 1.14 0.79 to 1.64 0.493
 Positive 80 (63.5) 12.5 52.5 18.8    
7th AJCC stage
 II 60 (47.6) 19.0 63.3 31.1 1.85 1.27 to 2.69 0.001
 III 66 (52.4) 10.6 47.0 10.6    
  1. LRFS local recurrence-free survival, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer