Variables | Subgroups | Pooled prevalence (% 95 CI) | Heterogeneity assessment | ||
---|---|---|---|---|---|
Isquare (%) | Q | P Heterogeneity | |||
ATM variant | All | 6% (4–8%) | 94 | 289 | 0.00 |
Deletion | 0% (0–1%) | 0 | 1 | 0.59 | |
Insertion | 2% (4–9%) | 67 | 3 | 0.08 | |
Substitution | 12% (7–18%) | 99 | 743 | 0.00 | |
BRCA status | Positive | 11% (7–15%) | 99 | 604 | 0.00 |
Negative | 3% (2–4%) | 85 | 107 | 0.00 | |
Not determined | 12% (6–18%) | 98 | 336 | 0.00 | |
Continents (population) | American | 9% (4–14%) | 96 | 125 | 0.00 |
Asian | 5% (1–11%) | 80 | 10 | 0.01 | |
European | 7% (5–8%) | 98 | 939 | 0.00 |