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Fig. 5 | Cancer Cell International

Fig. 5

From: Carcinogenic effect of adenylosuccinate lyase (ADSL) in prostate cancer development and progression through the cell cycle pathway

Fig. 5

RNA-seq reveals inactivation of cell cycle pathway after ADSL knockdown. a Volcano plot of differentially expressed genes (DEGs) with 665 up-regulated expression genes after ADSL knockdown. b KEGG pathway analysis for the DEGs in the siADSL and control cell lines. c GSEA analysis identified cell cycle pathway active in the control cell lines. d heat map presented many cell cycle related genes highly expressed in the control groups comparing to siADSL

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