Fig. 1

The clinical significance of miR-182-5p in patients with NPC. a The relative expression of miR-182-5p in 75 NPC tissues was measured by qRT-PCR. Dot plots present a comparison of miR-182-5p expression in NPC samples stratified by T classification (T1 + T2 vs. T3 + T4), N classification (N0 + N1 vs. N2 + N3), and Clinical Stage (I + II vs. III + IV). Data represent the mean ± SD. **p < 0.01, ***p < 0.001, Mann–Whitney test. b qRT-PCR for miR-182-5p was performed in the primary NPC samples without (LN−) or with (LN+) lymph node metastasis. p = 0.0070, Mann–Whitney test. c Actuarial probabilities were calculated using the Kaplan–Meier method and compared using the log-rank test (p = 0.013). Patients with high miR-182-5p expression had a significantly worse overall survival (OS) than those with low miR-182-5p expression