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Fig. 5 | Cancer Cell International

Fig. 5

From: Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration

Fig. 5

Downregulation of POLQ restrained HCC progression in vivo. A Tumor size was measured throughout animal experiments for calculating tumor volume and drawing tumor growth curve, showing the slower growth of tumors in shPOLQ group. B In vivo fluorescence imaging was performed before sacrificing animal to observe the tumor burden, which is represented by the fluorescence intensity. C Photos of tumors were taken after sacrificing the mice model and removing the xenografts. D Weight of xenografts was carried out, recorded and used for comparison between shCtrl and shPOLQ groups. E The expression of Ki67 was detected by IHC in xenografts obtained from shCtrl and shPOLQ groups, respectively. Data = mean ± SD (n ≥ 3). *** P < 0.001

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