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Table 2 Relationship between POLQ expression and tumor characteristics in patients with HCC

From: Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration

Features

No. of patients

POLQ expression

P value

low

high

All patients

80

47

33

 

Age (years)

   

0.114

 <51

40

20

20

 

 ≥51

40

27

13

 

Gender

   

0.206

 Male

65

36

29

 

 Female

15

11

4

 

Cirrhotic nodule

   

0.198

 No

11

7

4

 

 ≤3 mm

33

22

11

 

 >3 mm

36

18

18

 

Tumor number

   

0.001

 ≤1

65

44

21

 

 >1

15

3

12

 

Grade

   

0.831

 II

52

31

21

 

 III

28

16

12

 

Stage

   

0.681

 1

53

32

21

 

 2

27

15

12

 

T Infiltrate

   

0.681

 T1

53

32

21

 

 T2

27

15

12

 

Tumor recurrence

   

<0.001

 No

32

28

4

 

 Yes

48

19

29

 

Liver cirrhosis

   

0.443

 No

10

7

3

 

 Yes

70

40

30

 

HBsAg

   

0.725

 No

11

7

4

 

 Yes

69

40

29

 

HBcAb

   

0.299

 No

8

6

2

 

 Yes

70

39

31

 

Total bilirubin

   

0.863

 <17.1 μmol/L

59

35

24

 

 ≥17.1 μmol/L

21

12

9

 

ALT

   

0.013

 <40 μ/l

35

26

9

 

 ≥40 μ/l

45

21

24

 

Serum albumin

   

0.546

 <4 g/dl

22

12

10

 

 4 g/dl≤ALB<5.5 g/dl

57

34

23

 

 ≥5.5 g/dl

1

1

0

 

AFP

   

0.451

 <20 μg/l

23

12

11

 

 ≥20 μg/l

57

35

22

 

GGT

   

0.025

 <40 μ/l

23

18

5

 

 ≥40 μ/l

57

29

28

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