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Table 2 Relationship between POLQ expression and tumor characteristics in patients with HCC

From: Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration

Features No. of patients POLQ expression P value
low high
All patients 80 47 33  
Age (years)     0.114
 <51 40 20 20  
 ≥51 40 27 13  
Gender     0.206
 Male 65 36 29  
 Female 15 11 4  
Cirrhotic nodule     0.198
 No 11 7 4  
 ≤3 mm 33 22 11  
 >3 mm 36 18 18  
Tumor number     0.001
 ≤1 65 44 21  
 >1 15 3 12  
Grade     0.831
 II 52 31 21  
 III 28 16 12  
Stage     0.681
 1 53 32 21  
 2 27 15 12  
T Infiltrate     0.681
 T1 53 32 21  
 T2 27 15 12  
Tumor recurrence     <0.001
 No 32 28 4  
 Yes 48 19 29  
Liver cirrhosis     0.443
 No 10 7 3  
 Yes 70 40 30  
HBsAg     0.725
 No 11 7 4  
 Yes 69 40 29  
HBcAb     0.299
 No 8 6 2  
 Yes 70 39 31  
Total bilirubin     0.863
 <17.1 μmol/L 59 35 24  
 ≥17.1 μmol/L 21 12 9  
ALT     0.013
 <40 μ/l 35 26 9  
 ≥40 μ/l 45 21 24  
Serum albumin     0.546
 <4 g/dl 22 12 10  
 4 g/dl≤ALB<5.5 g/dl 57 34 23  
 ≥5.5 g/dl 1 1 0  
AFP     0.451
 <20 μg/l 23 12 11  
 ≥20 μg/l 57 35 22  
GGT     0.025
 <40 μ/l 23 18 5  
 ≥40 μ/l 57 29 28