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Fig. 2 | Cancer Cell International

Fig. 2

From: STAT3 pathway as a molecular target for resveratrol in breast cancer treatment

Fig. 2

Effects of Resveratrol on STAT3 Signaling Pathway in Breast Cancer Cells. Resveratrol can directly affect the STAT3 and its downstream molecular targets in breast cancer cells. Also, resveratrol can affect upstream regulators of STAT3 which results in changes in downstream molecular targets affecting the growth, progression and metastasis of breast cancer cells. Bcl-xL: B-cell lymphoma-extra large; MCL-1: Myeloid cell leukemia-1; TSG: tumor suppressor genes; COX-2: Cyclooxygenase-2; Akt: Protein kinase B (PKB) aka Akt

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