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Fig. 1 | Cancer Cell International

Fig. 1

From: LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancer

Fig. 1

LINC01605 is highly expressed in patients with CC. A the heatmap of the top 20 differentially expressed lncRNAs in GSE97300, GSE84983, GSE110715 and GSE70880, GSE75970 gene expression microarrays. B expression of LINC01605 in cancer and ADJ tissues of 134 CC patients were detected by RT-qPCR. C expression of LINC01605 in the TCGA-COAD database. D Kaplan–Meier analysis of the correlation between the expression of LINC01605 and the survival of COAD patients. E Kaplan–Meier analysis of the correlation between the expression of LINC01605 and the survival rate of 134 CC patients. F LINC01605 expression difference in tumor tissues of patients with recurrence or not measured using RT-qPCR. G analysis of the correlation between the expression of LINC01605 and the clinical phenotype of 134 patients. H Spearman’s correlation analysis of LINC01605 expression with the levels of CC markers CEA and CA199 in patients’ serum. I Cibersort analysis of the correlation between LINC01605 expression and immune cell infiltration in tumor tissues of COAD patients. Error bars represent means ± SD for three independent experiments (*p < 0.05, **p < 0.01 and ***p < 0.001, ns, not significant. paired or unpaired t test, one-way ANOVA, followed by Tukey’s multiple comparison)

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