Fig. 9From: LINC01605, regulated by the EP300-SMYD2 complex, potentiates the binding between METTL3 and SPTBN2 in colorectal cancerThe schematic figure. High expression of LINC01605, regulated by SMYD2/EP300-mediated H3K4me3 and H3K27ac modifications in CC, binds to METTL3 protein to promote the m6A modification of SPTBN2 mRNA and the translation of SPTBN2, which in turn leads to the development of CCBack to article page