Fig. 10From: Nestin is essential for cellular redox homeostasis and gastric cancer metastasis through the mediation of the Keap1–Nrf2 axisNestin knockdown inhibits xenograft GC tumorigenesis. The right back flank of 6-week-old BALB/c-nu mice (n = 8/group) were transfected with the subcutaneous injections of SGC-7901, SGC-7901-sh-NC, and SGC-7901-sh-SNHG11 cells. A The tumor size (growth rate) was determined over time. B Tumors were harvested 4 weeks after grafting and weighed. C Images of all tumors. D, E The mRNA and protein expression levels of Nestin in the tumor samples were determined using WB and qPCR, respectively, (n = 8). The results are expressed as means ± SD. *P < 0.05, **P < 0.01 vs. the indicated groupsBack to article page