|
Variables
|
Univariable model
|
Multivariable model
|
|---|
|
HR
|
95%CI
|
P-value
|
HR
|
95%CI
|
P-value
|
|---|
|
Training cohort (n = 203)
|
|
Age
|
(> 65)/ (≤ 65)
|
2.082
|
0.788–5.503
|
0.139
| | | |
|
Gender
|
Male/female
|
0.918
|
0.388–2.174
|
0.846
| | | |
|
T
|
(T3–4)/T2
|
1.884
|
0.648–5.475
|
0.244
| | | |
|
M
|
M1/M0
|
2.280
|
0.530–9.813
|
0.357
| | | |
|
N
|
(N1–3)/N0
|
2.743
|
1.285–5.854
|
0.009
|
2.244
|
1.019–4.940
|
0.045
|
|
Risk score
|
High/low
|
1.625
|
1.314–2.009
|
< 0.001
|
1.541
|
1.238–1.918
|
< 0.001
|
|
Testing cohort (n = 200)
|
|
Age
|
(> 65)/ (≤ 65)
|
1.458
|
0.697–3.051
|
0.317
| | | |
|
Gender
|
Male/female
|
0.454
|
0.217–0.948
|
0.037
|
0.510
|
0.241–1.079
|
0.078
|
|
T
|
(T3–4)/T2
|
2.673
|
1.023–6.988
|
0.045
| | | |
|
M
|
M1/ M0
|
2.427
|
0.574–10.273
|
0.228
| | | |
|
N
|
(N1–3)/N0
|
1.935
|
0.945–3.959
|
0.071
| | | |
|
Risk score
|
High/low
|
1.980
|
1.338–2.931
|
< 0.001
|
1.910
|
1.266–2.882
|
0.002
|
|
TCGA cohort (n = 403)
|
|
Age
|
(> 65)/(≤ 65)
|
1.629
|
0.915–2.901
|
0.098
| | | |
|
Gender
|
Male/female
|
0.635
|
0.364–1.108
|
0.109
| | | |
|
T
|
(T3–4)/T2
|
2.197
|
1.078–4.480
|
0.030
| | | |
|
M
|
M1/ M0
|
2.108
|
0.759–5.856
|
0.152
| | | |
|
N
|
(N1–3)/N0
|
2.222
|
1.325–3.725
|
0.002
|
1.657
|
0.932–2.944
|
0.085
|
|
Risk score
|
High/low
|
1.563
|
1.344–1.817
|
< 0.001
|
1.489
|
1.274–1.739
|
< 0.001
|
