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Fig. 2 | Cancer Cell International

Fig. 2

From: Long noncoding RNA LINC00958 suppresses apoptosis and radiosensitivity of colorectal cancer through targeting miR-422a

Fig. 2

LINC00958 promotes cell proliferation, suppresses cell apoptosis and radiosensitization of colorectal cancer. a The expression of LINC00958 in colorectal cancer cell lines. b The efficiencies of siRNA targeting LINC00958 and an overexpression plasmid of LINC00958 were detected. c The flow cytometry assay showed that knockdown of LINC00958 significantly increased the percentage of apoptosis. d, e The CCK-8 (d) and MTT (e) results indicated that si-LINC00958 decreased the ability of cell proliferation. f si-LINC00958 decreased the survival fraction under different irradiation dose. g The flow cytometry assay showed that overexpression of LINC00958 remarkably decreased the percentage of apoptosis. h and i The CCK-8 (h) and MTT (i) results indicated that overexpression of LINC00958 increased the ability of cell proliferation. j Overexpression of LINC00958 increased the survival fraction under different irradiation dose. Data are reported as means ± standard deviation of three independent experiments. *p < 0.05, **p < 0.01

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