Fig. 2

GACAT3 controls cell proliferation and apoptosis in cultured ESCC cells. A GACAT3 expression was knocked down by shRNA targeting GACAT3 in KYSE-150 and KYSE-510 cells. Effects of GACAT3 on cell proliferation, examined by (B) CCK-8, C Edu and D colony formation assays. E Cell cycle and F apoptotic rates of ESCC cells after transfection with GACAT3, examined by FACS analysis. *P < 0.05, **P < 0.01, ***P < 0.001