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Fig. 1 | Cancer Cell International

Fig. 1

From: Knockdown of PGM1 enhances anticancer effects of orlistat in gastric cancer under glucose deprivation

Fig. 1

PGM1 expression is negatively correlated with survival outcome of GC patients and overexpressed in GC. a, b OS (a) and PFS (b) of GC patients at III stage who were divided into low-PGM1 and high-PGM1 groups according to the Kaplan–Meier plotter database. c, d OS (c) and PFS (d) of patients with poorly differentiated GC who were divided into low-PGM1 and high-PGM1 groups according to the Kaplan–Meier plotter database. e, f OS (e) and PFS (f) of patients with the intestinal type of GC who were divided into low-PGM1 and high-PGM1 groups according to the Kaplan–Meier plotter database. g qRT-PCR analysis to analyze PGM1 mRNA expression in 40 pairs of GC and adjacent noncancerous tissues. h IHC analysis to detect PGM1 expression in 40 pairs of GC and adjacent noncancerous tissues. IHC images of two cases are shown on the left and the corresponding diagram of 40 cases are on the right. Scale bar: 100 μm. i WB analysis to show the PGM1 expression between GC and gastric epithelial cell lines. Data are shown as the mean ± SD. **P < 0.01. GC: gastric cancer; PGM1: Phosphoglucomutase 1; HR: hazard ratio; OS: overall survival; PFS: progression-free survival; qRT-PCR: quantitative real-time PCR; WB: western blot; IHC: immunohistochemistry; SD: standard deviation

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