Table 2 Characteristics of patients of individual studies included in the qualitative systemic review
First author | Year | BRCA1/BRCA2 | No. with PT (BRCA1/2) | No. with no PT (BRCA1/2) | Mean age at UBC diagnosis (PT/NPT) | Mean age at PT | Stage | Interval |
|---|---|---|---|---|---|---|---|---|
van Sprundel [17] | 2005 | 115/43 | 79(60/19) | 69(55/14) | 38.0/39.4 | 41.9 | I-III | 4.0 ± 0.5 |
Kiely [11] | 2009 | 161/127 | 154 | 864 | 46.7 | NR | I-III | NR |
Evans [10] | 2013 | NR | 105(51/54) | 593 (NR) | 40.3/44.5 | 44 | I-III | 1.1(0.0-13.3) |
Evans [10] (matched)a | 2013 | 102/108 | 105(51/54) | 105(51/54) | 40.3/41.5 | 44 | I-III | 1.1(0.0-13.3) |
Metcalfe [18] | 2014 | 226/158 | 181(103/76) | 209(123/82) | 43.6/41.3 | NR | I-II | 2.3 |
Heemskerk- Gerritsen [19] | 2015 | 454/129 | 242(193/49) | 341(261/80) | 38/42 | NR | I-III | 2.0(0-20.2) |
Fachinetti [35] | 2019 | 70/58b | NR | NR | 44 | NR | NR | NR |
Evron [36] | 2019 | 81/81 | 54/29 | 59/22 | NR | 50.4 | I-III | NR |