Cancer Cell International

Table 3 The core targets of merged network (HLJDD potential active ingredients related targets-OSCC related targets protein–protein interaction network)

From: Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation

Name	Degree value	Name	Degree value	Name	Degree value
RNF2	61	SHC1	59	RELA	75
GRB2	87	ABL1	66	HSP90AB1	86
NR3C1	71	CΜL1	73	PARP1	64
MDM2	93	STAT3	65	JUN	77
CREBBP	73	BRCA1	93	PML	59
COPS5	75	HUWE1	72	AKT1	72
SRC	75	MAPK1	60	CTNNB1	78
UBC	93	NTRK1	152	CDK1	56
UBE2I	70	EEF1A1	55	TP53	225
PCNA	55	EGFR	126	CDK2	102
EP300	97	IKBKG	61	EWSR1	64
AR	195	XPO1	64	CDKN1A	64
APP	80	YWHAZ	79	TRAF6	66
SP1	59	HNRNPK	54	SMAD3	70
YWHAQ	54	HNRNPU	54	ESR1	144
HDAC1	73	HSPA5	67	MYC	94
VCP	79	HSP90AA1	101
TUBB	67	RB1	67

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ISSN: 1475-2867

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