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Table 3 The core targets of merged network (HLJDD potential active ingredients related targets-OSCC related targets protein–protein interaction network)

From: Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation

Name Degree value Name Degree value Name Degree value
RNF2 61 SHC1 59 RELA 75
GRB2 87 ABL1 66 HSP90AB1 86
NR3C1 71 CΜL1 73 PARP1 64
MDM2 93 STAT3 65 JUN 77
CREBBP 73 BRCA1 93 PML 59
COPS5 75 HUWE1 72 AKT1 72
SRC 75 MAPK1 60 CTNNB1 78
UBC 93 NTRK1 152 CDK1 56
UBE2I 70 EEF1A1 55 TP53 225
PCNA 55 EGFR 126 CDK2 102
EP300 97 IKBKG 61 EWSR1 64
AR 195 XPO1 64 CDKN1A 64
APP 80 YWHAZ 79 TRAF6 66
SP1 59 HNRNPK 54 SMAD3 70
YWHAQ 54 HNRNPU 54 ESR1 144
HDAC1 73 HSPA5 67 MYC 94
VCP 79 HSP90AA1 101   
TUBB 67 RB1 67