Fig. 2From: Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressivenessDDR1 expression in different subcellular compartments of cancerous and adjacent benign tissue of low and high GS tumors. DDR1 immunostaining in membrane (A), nucleus (B), and cytoplasm (C) of tumor areas corresponding to low (≤ 7 [3 + 4]) and high (≥ 7 [4 + 3]) GS scores. Levels of DDR1 expression in the different subcellular compartments of cancerous areas were defined as positive (OSP > 0%) or negative (OSP = 0%), as described in the Methods section. Only positive samples are displayed. The association between DDR1 expression and GS category was tested using Fisher’s exact test in each tissue type, cancerous or adjacent benign, respectively. p values lower than 0.05 denote statistically significant differencesBack to article page